dominant negative mutants中文

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2 ) the growth curves for different cells show that overexpression of gpil7p has no lethal effect on the yeast cells and only that of the dominant negative mutants can cause cells not grow
2 )生長曲線的測定表明，過表達gpi17p對正常酵母細胞不致死，而只有顯性負性突變體的過表達才會導致酵母細胞不能生長。
Interestingly , inhibition of p38 mapk activation ( but not erk activation ) by its inhibitors or by expression of a dominant negative mutant of p38 mapk could effectively block the chemotactic effect of ( - arrestin2
P38mapk上游激酶ask1的顯性失活突變體也可以阻斷- arrestin2對趨化的增強作用。這說明是p38mapk而不是erk信號通路與- arrestin2對趨化的增強作用相關。
3 ) foa ( fluoroorotic acid ) treatment with the dominant negative mutants showed that the dominant negative effects of mutants were caused by the presence of the gpi17 vector , not by another mutation located somewhere in the genome and in a gene involved in the natural resistance against copper
3 ) foa ( 5 -氟-乳清酸)處理突變體細胞表明，得到的顯性負性突變體不是細胞中銅抗性基因突變的產物，其確為gpi17突變引起。

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